THE FE65 PROTEIN AND THE MOLECULAR BASIS OF THE FAMILIAL ALZHEIMER’S DISEASE: CHARACTERIZATION OF ITS ROLE IN THE BETA-AMYLOID PEPTIDE GENERATION AND IN THE PATHWAYS INVOLVING THE BETA-AMYLOID PRECURSOR PROTEIN
- 3 Anni 1997/2000
- 108.456€ Totale Fondi
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Pubblicazioni Scientifiche
- 1998 FEBS LETTERS
Fe65 and the protein network centered around the cytosolic domain of the Alzheimer's beta-amyloid precursor protein
- 1998 BIOCHEMICAL JOURNAL
Fe65L2: a new member of the Fe65 protein family interacting with the intracellular domain of the Alzheimer's beta-amyloid precursor protein
- 1997 JOURNAL OF BIOLOGICAL CHEMISTRY
The WW domain of neural protein FE65 interacts with proline-rich motifs in Mena, the mammalian homolog of Drosophila enabled
- 1997 BIOCHEMICAL JOURNAL
DNA-binding protein Pur alpha and transcription factor YY1 function as transcription activators of the neuron-specific FE65 gene promoter
- 2001 JOURNAL OF BIOLOGICAL CHEMISTRY
The beta-amyloid precursor protein functions as a cytosolic anchoring site that prevents Fe65 nuclear translocation
- 1998 JOURNAL OF BIOLOGICAL CHEMISTRY
The Fe65 adaptor protein interacts through its PID1 domain with the transcription factor CP2/LSF/LBP1
